As you may have deduced from the name, the MatroxTripleHead2Go allows you to run three monitors off of a single graphics card. It's similar to the DualHead2Go, but with one important improvement.
One thing that Matrox learned from their experiences with the DualHead2Go is that many of the people who bought it were interested in playing games over multiple monitors. As I and many other reviewers found out, it wasn't necessarily suited for this task. While the Windows desktop easily stretched across multiple monitors, it was more difficult to get full-screen DirectX games to do so. Many games simply wouldn't allow the user to select such an odd wide-screen resolution, and would instead simply show the same screen on both monitors.
How does it match up against its dual-head predecessor?

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